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biological source
human lymph
growth mode
Suspension
karyotype
46,XY.ish dup(21)(q21)(RP11-15D13++,RP11-66H5++)
morphology
Lymphoblastoid
products
Not specified
receptors
Not specified
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cancer
shipped in
dry ice
storage temp.
−196°C
Related Categories
Cell Line Origin
Human EBV transformed lymphocytes Alzheimer
Cell Line Description
Derived from a patient with early onset Alzheimer disease and cerebral amyloid angiopathy (CAA), carrying a 6.5 Mb microduplication of the APP gene locus on chromosome 21. This is an EBV-transformed lymphoblastoid cell line.
Culture Medium
RPMI 1640 + 2mM Glutamine + 20% Foetal Bovine Serum (FBS).
Subculture Routine
Maintain cultures between 300,000 to 900,000 cells/ml; 5% CO2; 37°C
Other Notes
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Certificates of Analysis (COA)
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