A6608
Albumin human
recombinant, expressed in Saccharomyces cerevisiae, aqueous solution, 10% in aqueous buffer, ≥99% (agarose gel electrophoresis)
Synonym(s):
rHSA
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About This Item
Empirical Formula (Hill Notation):
C2936H4624N786O889S41
CAS Number:
Molecular Weight:
66471.53
MDL number:
UNSPSC Code:
12352202
eCl@ss:
42010201
NACRES:
NA.25
biological source
human
Quality Level
recombinant
expressed in Saccharomyces cerevisiae
Assay
≥99% (agarose gel electrophoresis)
form
aqueous solution
mol wt
monomer ~67 kDa
concentration
10% in aqueous buffer
technique(s)
cell culture | mammalian: suitable
UniProt accession no.
storage temp.
2-8°C
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
Gene Information
human ... ALB(213)
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General description
Albumin constitutes 25% of the proteins produced by the liver and is a prominent protein found in the blood. It is a protein of a single polypeptide chain with a thiol group.
Application
Albumin human has been used:
- to study its adsorption process on model mica surface at pH 3.5 using the atomic force microscopy (AFM) and in situ streaming potential measurements
- to study its proteolytic activities under reducing conditions
- in the medium for stem cell cultivation
This recombinant variant is recommended for use in absorption, distribution, metabolism, and excretion (ADME) pharmacological research; cell culture; drug delivery research; and cryopreservation of cells.
Biochem/physiol Actions
Albumin is a binding and transport protein that serves as a protein repository and a carrier for amino acids. Albumin binding dissolves the biomolecules in blood and ensures its effective transport. This also prevents the loss of substance through excretion. Pathological conditions like vasculitis, lymphangiectasia, glomerulonephritis, and hepatic sinusoidal hypertension might result in hypoalbuminemia. This product can be used in the pharmaceutical industry as a drug excipient and to coat medical devices.
Albumins are soluble monomeric proteins found in the body fluids and tissues of animals and in some plant seeds. Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones. Serum albumins are also vital in regulating the colloidal osmotic pressures of blood.
Analysis Note
Endotoxin tested
Other Notes
View more information on human serum albumin.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Learn more about the cell culture supplements human serum albumin (HSA) and recombinant human serum albumin (rHSA). Explore their applications in cell culture and beyond.
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