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Key Documents

A3159

Sigma-Aldrich

Adenine hemisulfate salt

powder, BioReagent, suitable for cell culture

Synonym(s):

6-Aminopurine hemisulfate salt, Adenine sulfate salt

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About This Item

Linear Formula:
C5H5N5 · 1/2H2SO4
CAS Number:
Molecular Weight:
184.17
Beilstein:
3820263
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.75

biological source

synthetic (organic)

Quality Level

product line

BioReagent

Assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

solubility

0.5 M HCl: 10 mg/mL

SMILES string

OS(O)(=O)=O.Nc1ncnc2[nH]cnc12.Nc3ncnc4[nH]cnc34

InChI

1S/2C5H5N5.H2O4S/c2*6-4-3-5(9-1-7-3)10-2-8-4;1-5(2,3)4/h2*1-2H,(H3,6,7,8,9,10);(H2,1,2,3,4)

InChI key

LQXHSCOPYJCOMD-UHFFFAOYSA-N

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General description

Adenine is a component of DNA, RNA, cofactors nicotinamide adenine dinucleotide (NAD). It is also part of flavin adenine dinucleotide (FAD) and signaling molecules cyclic adenosine monophosphate(cAMP).

Application

Adenine hemisulfate salt has been used:
  • as component of auxotrophy selection reagent for yeast culture
  • as essential nutrient to improve yeast transformation efficiency
  • as a component of synthetic complete (SC) medium for yeast culture

Pictograms

Skull and crossbones

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Eye Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Effect of preorganization on the affinity of synthetic DNA binding motifs for nucleotide ligands
Vollmer S and Richert C
Organic & Biomolecular Chemistry, 13(20), 5734-5742 (2015)
Mating based split-ubiquitin assay for detection of protein interactions
Horaruang W and Zhang B
Bio-protocol, 7, e2258-e2258 (2017)
Base-resolution stratification of cancer mutations using functional variomics
Yi S, et al.
Nature Protocols, 12(11), 2323-2323 (2017)
Nutrient supplements boost yeast transformation efficiency.
Yu SC, et al.
Scientific Reports, 6, 35738-35738 (2016)
Katherine D Bauman et al.
Cell chemical biology, 26(5), 724-736 (2019-03-12)
The disconnect between the genomic prediction of secondary metabolite biosynthetic potential and the observed laboratory production profile of microorganisms is well documented. While heterologous expression of biosynthetic gene clusters (BGCs) is often seen as a potential solution to bridge this

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