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905

Sigma-Aldrich

Naphthol AS-D Chloroacetate

Synonym(s):

Naphthol AS-D chloroacetate, 3-Hydroxy-2-naphthoic-o-toluidide chloroacetate

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About This Item

Empirical Formula (Hill Notation):
C20H16ClNO3
CAS Number:
35245-26-2
Molecular Weight:
353.80
EC Number:
252-463-5
MDL number:
MFCD00042714
UNSPSC Code:
12352204
PubChem Substance ID:
329769916
NACRES:
NA.47

form

powder

Quality Level

500

IVD

for in vitro diagnostic use

application(s)

hematology
histology

shipped in

dry ice

storage temp.

−20°C

SMILES string

Cc1ccccc1NC(=O)c2cc3ccccc3cc2OC(=O)CCl

InChI

1S/C20H16ClNO3/c1-13-6-2-5-9-17(13)22-20(24)16-10-14-7-3-4-8-15(14)11-18(16)25-19(23)12-21/h2-11H,12H2,1H3,(H,22,24)

InChI key

FMVKYSCWHDVMGO-UHFFFAOYSA-N

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Components

Gelatin capsules contain 20 mg

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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Grace F D'Costa et al.
Indian journal of medical sciences, 61(3), 152-155 (2007-03-06)
Granulocytic sarcoma is a rare extramedullary tumor composed of immature myeloid cells. It is usually associated with leukemia or other myeloproliferative disorders but can also occur without overt hematologic diseases. The breast is an uncommon site of presentation and requires
S Jolly et al.
Journal of comparative pathology, 122(2-3), 155-162 (2000-02-24)
The presence of chymase-like proteinase in bovine mast cells was investigated by an enzyme-histochemical technique (naphthol-AS-D-chloroacetate as substrate) in normal skin, primary bronchus, lung and duodenum. The counts and distribution of chymase-positive and toluidine blue-positive mast cells were compared by
M G Braun et al.
Hematological oncology, 14(2), 83-90 (1996-06-01)
Enzyme histochemistry for naphthol ASD chloroacetate (NASDCA, 'Leder's stain') is used to identify the granulocyte lineage ranging from promyelocytes to mature neutrophils and is an additional tool for the characterization of leukemias. We demonstrated for the first time that NASDCA
H Ruokonen
Acta dermato-venereologica, 72(2), 92-94 (1992-01-01)
We compared the number of mast cells in erythema multiforme lesions, in clinically healthy mucosa between the EM attacks and in healthy mucosa from healthy volunteers. The mast cell count in patients with erythema multiforme was numerically higher than in
U Schmidt et al.
British journal of haematology, 68(2), 175-180 (1988-02-01)
In chronic granulocytic leukaemia, hybridoid leucocytes can regularly be found. Light microscopically they contain a mixture of eosinophilic, basophilic and naphthol AS-D chloroacetate esterase-positive granules. The present study was done to clarify the ultrastructural composition of these cells. It could
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