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61764

Sigma-Aldrich

Lectin from Phaseolus vulgaris

lyophilized, powder

Synonym(s):

PHA, Red kidney bean Agglutinin

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About This Item

EC Number:
232-718-7
MDL number:
MFCD00165256
UNSPSC Code:
12352202
NACRES:
NA.56

biological source

Phaseolus vulgaris

Assay

≥70% (biuret)

form

powder

quality

lyophilized

mol wt

Mr ~128000

technique(s)

tissue culture: suitable

storage temp.

2-8°C

General description

Lectins are distinct proteins or glycoproteins that have at least one non-catalytic domain which fixes reversibly to a definite mono- or oligosaccharide. Some of their potentially utilizable biological assets include: antitumor, immunomodulatory and anti-insect, antifungal, antibacterial, anti-HIV, and mitogenic properties.

Application

Lectin was used in isolation and culture of optimized peripheral blood mononuclear cells (PBMCs).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Arishya Sharma et al.
Journal of biomedicine & biotechnology, 2009, 929568-929568 (2009-04-04)
A lectin has been isolated from seeds of the Phaseolus vulgaris cv. "Anasazi beans" using a procedure that involved affinity chromatography on Affi-gel blue gel, fast protein liquid chromatography (FPLC)-ion exchange chromatography on Mono S, and FPLC-gel filtration on Superdex
Marsha Feske et al.
Clinical and vaccine immunology : CVI, 15(10), 1616-1622 (2008-08-30)
Children and immunocompromised adults are at an increased risk of tuberculosis (TB), but diagnosis is more challenging. Recently developed gamma interferon (IFN-gamma) release assays provide increased sensitivity and specificity for diagnosis of latent TB, but their use is not FDA
Lok R Joshi et al.
Frontiers in immunology, 12, 747574-747574 (2021-11-23)
Swine influenza is a highly contagious respiratory disease of pigs caused by influenza A viruses (IAV-S). IAV-S causes significant economic losses to the swine industry and poses challenges to public health given its zoonotic potential. Thus effective IAV-S vaccines are
Sunita Yadav et al.
Cellular immunology, 361, 104272-104272 (2021-01-15)
Visceral leishmaniasis (VL) is a potentially fatal parasitic disease causing high morbidity and mortality in developing countries. Vaccination is considered the most effective and powerful tool for blocking transmission and control of diseases. However, no vaccine is available so far
Silvia Cerboni et al.
The Journal of experimental medicine, 214(6), 1769-1785 (2017-05-10)
Activation of the cyclic dinucleotide sensor stimulator of interferon (IFN) genes (STING) is critical for IFN and inflammatory gene expression during innate immune responses. However, the role of STING in adaptive immunity is still unknown. In this study, we show

Articles

Lectin Selection Guide: A Useful Guide for Selecting the Right Lectin

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