27667

Collagenase Chromophore-Substrate

chromogenic, powder or crystals

• Synonym(s): 4-Phenylazobenzyloxycarbonyl-Pro-Leu-Gly-Pro-D-Arg-OH dihydrate
• Empirical Formula (Hill Notation): C₃₈H₅₂N₁₀O₈ · 2H₂O
• CAS Number: 118081-33-7
• Molecular Weight: 812.91
• EC Number: 241-086-1
• MDL number: MFCD00151529
• UNSPSC Code: 12352204
• PubChem Substance ID: 329753009
• NACRES: NA.32

Properties

• product name: Collagenase Chromophore-Substrate, for use at 320 nm
• description: for quantitative collagenase determination
• form: powder or crystals
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: O.O.CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)OCc2ccc(cc2)\N=N\c3ccccc3)C(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@H](CCCNC(N)=N)C(O)=O
• InChI: 1S/C38H52N10O8.2H2O/c1-24(2)21-29(33(50)42-22-32(49)47-19-7-12-30(47)34(51)43-28(36(53)54)11-6-18-41-37(39)40)44-35(52)31-13-8-20-48(31)38(55)56-23-25-14-16-27(17-15-25)46-45-26-9-4-3-5-10-26;;/h3-5,9-10,14-17,24,28-31H,6-8,11-13,18-23H2,1-2H3,(H,42,50)(H,43,51)(H,44,52)(H,53,54)(H4,39,40,41);2*1H2/b46-45+;;/t28-,29+,30+,31+;;/m1../s1
• InChI key: PZUVBRODNGRBBH-UHGWVMIQSA-N

Description

Biochem/physiol Actions

Collagenase chromophore-substrate is specifically cleaved by collagenase between the leucine and glycine residues. Digestion of the colored hydrophilic substrate leads to the colored fragment PAZ-Pro-Leu-OH (II) and the colorless tripeptide H-GJy-Pro-D-Arg-OH (III).

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves