T4764

Δ⁹-Tetrahydrocannabinol solution

1.0 mg/mL in methanol, analytical standard, for drug analysis

• Synonym(s): Δ¹-Tetrahydrocannabinol
• Empirical Formula (Hill Notation): C₂₁H₃₀O₂
• CAS Number: 1972-08-3
• Molecular Weight: 314.46
• EC Number: 200-659-6
• MDL number: MFCD00083207
• UNSPSC Code: 41116107
• PubChem Substance ID: 329826800
• NACRES: NA.24

Properties

• grade: analytical standard, for drug analysis
• Quality Level: 200
• drug control: Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
• concentration: 1.0 mg/mL in methanol
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• application(s): pharmaceutical (small molecule)
• format: single component solution
• storage temp.: 2-8°C
• SMILES string: [H][C@@]12CCC(C)=C[C@@]1([H])c3c(O)cc(CCCCC)cc3OC2(C)C
• InChI: 1S/C21H30O2/c1-5-6-7-8-15-12-18(22)20-16-11-14(2)9-10-17(16)21(3,4)23-19(20)13-15/h11-13,16-17,22H,5-10H2,1-4H3/t16-,17-/m1/s1
• InChI key: CYQFCXCEBYINGO-IAGOWNOFSA-N
• Gene Information: human ... CNR1(1268) , CNR2(1269) ; mouse ... Cnr1(12801) ; rat ... Cnr1(25248)

Description

General description

Δ⁹-Tetrahydrocannabinol, known as THC, is a C₂₁ terpenophenolic compound and is the primary psychoactive cannabinoid present in cannabis and hemp.

Application

The Δ⁹-Tetrahydrocannabinol analytical standard can be used as follows:

• Development and validation of a high-performance liquid chromatographic method coupled with UV detection to measure cannabidiol and ∆⁹-tetrahydrocannabinol in rat plasma samples following their extraction by protein precipitation and liquid-liquid extraction (LLE)
• Estimation of cannabidiol and ∆⁹-tetrahydrocannabinol extracted from human plasma samples by liquid-liquid extraction using ultra-performance liquid chromatography with triple quadrupole mass spectrometry
• Multi-residue analysis of Δ⁹-tetrahydrocannabinol (THC) and its two degradation products, 11-hydroxy-Δ⁹-tetrahydrocannabinol and 11-nor-9-carboxy-Δ⁹-tetrahydrocannabinol, in whole blood samples by QuEChERS extraction and gas chromatography (GC) coupled with tandem mass spectrometry (MS/MS)
• Optimization of an ultra-high performance supercritical fluid chromatographic (UHPSFC) method, combined with a tandem mass spectrometer (MS/MS) to determine ∆⁹-tetrahydrocannabinol, along with three of its major metabolites and four synthetic metabolites in wastewater samples following liquid-liquid extraction
• Development and validation of an ultra high-performance liquid chromatographic (UHPLC) method coupled to photodiode array and mass spectrometry detectors to determine 11 cannabinoids in various Cannabis Sativa samples

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• Pictograms: GHS02,GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H225 - H301 + H311 + H331 - H370
• Precautionary Statements: P210 - P233 - P280 - P301 + P310 - P303 + P361 + P353 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 49.5 °F - closed cup
• Flash Point(C): 9.7 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves