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Key Documents

77699

Sigma-Aldrich

2-Phenoxyethanol

≥99%

Synonym(s):

Ethylene glycol monophenyl ether, Phenylglycol

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About This Item

Linear Formula:
C6H5OCH2CH2OH
CAS Number:
Molecular Weight:
138.16
Beilstein:
1364011
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥99%

form

viscous liquid

refractive index

n20/D 1.539

bp

244-246 °C

mp

11-13 °C

solubility

soluble, clear

density

1.107 g/mL at 20 °C (lit.)

functional group

hydroxyl

SMILES string

OCCOc1ccccc1

InChI

1S/C8H10O2/c9-6-7-10-8-4-2-1-3-5-8/h1-5,9H,6-7H2

InChI key

QCDWFXQBSFUVSP-UHFFFAOYSA-N

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General description

2-Phenoxyethanol is used as a fish anesthetic agent.

Application

2-Phenoxyethanol may be used as a starting material to synthesize diorganodiselenides derivatives. It can undergo aromatic alkylation with fluoren-9-one to form 9,9-bis[4-(2-hydroxyethoxy)phenyl]fluorene in the presence of Ti4+ cation-exchanged montmorillonite catalyst.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

258.8 °F - closed cup

Flash Point(C)

126 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Efficacy of 2-phenoxyethanol as an anaesthetic for adult redline torpedo fish, Sahyadria denisonii (day 1865).
Varkey T
International Journal of Zoology (2014)
Simple and clean synthesis of 9, 9-bis [4-(2-hydroxyethoxy) phenyl] fluorene from the aromatic alkylation of phenoxyethanol with fluoren-9-one catalysed by titanium cation-exchanged montmorillonite.
Ebitani K
Green Chemistry, 2(4), 157-160 (2000)
Anaesthetic qualities of eugenol and 2-phenoxyethanol and their effect on some haematological parameters in farmed European sea bass (Dicentrarchus labrax L.).
Filiciotto F
Journal of Animal and Veterinary Advances, 11, 494-502 (2012)
Mehmet Çağrı Akgündüz et al.
Scientific reports, 10(1), 1209-1209 (2020-01-29)
In this study, the toxic effects of phenoxyethanol (Phy-Et), which is widely used in cosmetic industry, has been investigated with Allium test by means of physiological, cytogenetic, anatomical and biochemical parameters. To determine the changes in physiological reactions weight gain
Validation of HPLC analysis of 2-phenoxyethanol, 1-phenoxypropan-2-ol, methyl, ethyl, propyl, butyl and benzyl 4-hydroxybenzoate (parabens) in cosmetic products, with emphasis on decision limit and detection capability.
Borremans M, et al.
Chromatographia, 59(1-2), 47-53 (2004)

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