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00942

Supelco

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide

for GC derivatization, LiChropur™, ≥95.0% (GC), with 1% tert-Butyldimethylchlorosilane

Synonym(s):

N-Methyl-N-tert-butyldimethylsilyltrifluoroacetamide, MTBSTFA + 1% TBDMSCl, Silylating mixture VI

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About This Item

Empirical Formula (Hill Notation):
C9H18F3NOSi
CAS Number:
77377-52-7
Molecular Weight:
241.33
Beilstein:
3606546
MDL number:
MFCD00009671
UNSPSC Code:
41116105
PubChem Substance ID:
329747171
NACRES:
NA.22

product name

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane, for GC derivatization, LiChropur™, ≥95.0% (GC)

grade

for GC derivatization

Quality Level

100

Assay

≥95.0% (GC)

form

liquid

quality

LiChropur™

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

impurities

0.5-1.5% tert-butyldimethylchlorosilane

storage temp.

2-8°C

SMILES string

CN(C(=O)C(F)(F)F)[Si](C)(C)C(C)(C)C

InChI

1S/C9H18F3NOSi/c1-8(2,3)15(5,6)13(4)7(14)9(10,11)12/h1-6H3

InChI key

QRKUHYFDBWGLHJ-UHFFFAOYSA-N

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General description

N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamidewith 1% tert-Butyldimethylchlorosilane (TBDMS) is a derivatizing reagentcommonly used in gas chromatography (GC) and gas chromatography-massspectrometry (GC-MS).

Application

MTBSTFA + 1% TBDMSCl can be used as a derivatizing reagentin the analysis of:
  • Organic acid profile in human serum by gaschromatography/mass spectrometry (GC/MS).
  • Nerveagents and their breakdown products by GC–MS-MS method.

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Discover LiChropur™ reagents ideal for HPLC or LC-MS analysis

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

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Product No.
Description
Pricing

Pictograms

FlameExclamation mark
GHS02,GHS07

Signal Word

Warning

Hazard Statements

H226,H315,H319

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

113.0 °F - closed cup

Flash Point(C)

45 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCCG8048
BCCF1600
BCCC7518
BCCB1053
BCBW7248

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Mass spectrometry of anabolic steroids as their tert-butyldimethylsilyl ether derivatives.
Steffenrud, S.
Rapid Communications in Mass Spectrometry, 10, 1698-1702 (1996)
Yalun Arifin et al.
Applied microbiology and biotechnology, 98(21), 9033-9044 (2014-08-16)
Sugarcane is the most efficient large-scale crop capable of supplying sufficient carbon substrate, in the form of sucrose, needed during fermentative feedstock production. However, sucrose metabolism in Escherichia coli is not well understood because the two most common strains, E.
François Leclerc et al.
Hypertension in pregnancy, 33(3), 341-348 (2014-04-15)
We aimed to investigate potential association between the exposure of bisphenol A (BPA) and preeclampsia. Concentrations of BPA were assessed in 58 pregnancies including 35 normotensive and 23 preeclamptic women, using a highly sensitive gas chromatography-mass spectrometry (GC-MS) method. BPA
Xue Shi et al.
Journal of proteome research, 14(2), 1174-1182 (2015-01-17)
The interactions among the gut, liver, and immune system play an important role in liver disease. Probiotics have been used for the treatment and prevention of many pathological conditions, including liver diseases. Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC-TOF
Tsubasa Nakajima et al.
Plant & cell physiology, 55(9), 1605-1612 (2014-06-28)
Cyanobacteria have flexible metabolic capability that enables them to adapt to various environments. To investigate their underlying metabolic regulation mechanisms, we performed an integrated analysis of metabolic flux using transcriptomic and metabolomic data of a cyanobacterium Synechocystis sp. PCC 6803
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