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Key Documents

1.01806

SAFC

Benzyl benzoate

EMPROVE® EXPERT, Ph. Eur., BP, JP, USP

Pharma Manufacturing

Synonym(s):

Benzyl benzoate, Benzoic acid benzyl ester

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About This Item

Empirical Formula (Hill Notation):
C14H12O2
CAS Number:
Molecular Weight:
212.24
MDL number:
UNSPSC Code:
12352108
EC Index Number:
204-402-9

Agency

BP
JP
Ph. Eur.
USP

Quality Level

vapor pressure

<0.1 hPa ( 25 °C)

product line

EMPROVE® EXPERT

form

liquid

autoignition temp.

480 °C

bp

324 °C/1013 hPa

mp

21 °C

transition temp

flash point 158 °C

density

1.12 g/cm3 at 20 °C

application(s)

liquid formulation
parenterals
pharmaceutical
solid formulation

storage temp.

15-25°C

InChI

1S/C14H12O2/c15-14(13-9-5-2-6-10-13)16-11-12-7-3-1-4-8-12/h1-10H,11H2

InChI key

SESFRYSPDFLNCH-UHFFFAOYSA-N

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Benzylbenzoate is the ester of benzoic acid and benzyl alcohol. Due to its antimicrobial characteristics, it is typically used as preservative in pharmaceutical formulations and cosmetics. It is also used as a solvent in cosmetic preparations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

related product

Pictograms

Exclamation markEnvironment

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

298.4 °F - closed cup

Flash Point(C)

148 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Find key considerations for the selection and use of preservatives in a range of different therapeutic applications including topical, oral, transmucosal, inhalation, and otic, as well as injectables.

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