R-035

Rufinamide-¹⁵N,D₂ solution

100 μg/mL (Acetonitrile:Water (90:10) (v/v)), certified reference material, ampule of 1 mL, Cerilliant^®

• Empirical Formula (Hill Notation): C₁₀H₆D₂F₂N₃¹⁵NO
• Molecular Weight: 241.20
• UNSPSC Code: 41116107

Properties

• grade: certified reference material
• Quality Level: 300
• form: liquid
• feature: Snap-N-Spike^®/Snap-N-Shoot^®
• packaging: ampule of 1 mL
• manufacturer/tradename: Cerilliant^®
• concentration: 100 μg/mL (Acetonitrile:Water (90:10) (v/v))
• technique(s): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• application(s): clinical testing
• format: single component solution
• storage temp.: 2-8°C

Description

Application

• Rufinamide for Epilepsy Research: Utilizing rufinamide in therapeutic drug monitoring, a study enhanced the understanding of drug levels in epilepsy treatment using mass spectrometry, aligning with practices in neurology research and pharmaceutical quality control (Kim et al., 2024).


• Pharmacokinetics of Rufinamide: A network meta-analysis of randomized, placebo-controlled trials evaluated the efficacy, tolerability, and safety of third-generation antiseizure medications, including rufinamide, underscoring its role in global epilepsy treatment strategies (Chen et al., 2024).


• Rufinamide in Neuropharmacology: Research on the inhibition of resurgent Na(+) currents by rufinamide contributes to the understanding of its mechanism in neurological pathways, aiding in the development of targeted epilepsy treatments (Chen and Kuo, 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Snap-N-Shoot is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS02,GHS07
• Signal Word: Danger
• Hazard Statements: H225 - H302 + H312 + H332 - H319
• Precautionary Statements: P210 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2
• Storage Class Code: 3 - Flammable liquids
• WGK: WGK 2
• Flash Point(F): 42.8 °F - closed cup
• Flash Point(C): 6.0 °C - closed cup