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Key Documents

C-216

Supelco

Cortisol-13C3 solution

100 μg/mL in methanol, certified reference material, ampule of 1 mL, Cerilliant®

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About This Item

Empirical Formula (Hill Notation):
C1813C3H30O5
CAS Number:
Molecular Weight:
365.44
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

Application


  • Automated analysis of cortisol metabolites using Cortisol-¹³C₃: An innovative method utilizing online in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry was developed for the automated analysis of sulfated steroid metabolites in saliva samples, including those labeled with Cortisol-¹³C₃. This technique provides a robust tool for biochemical research focused on hormone analysis and metabolic studies (Kataoka and Nakayama, 2022).

  • Validation of LC-MS/MS methods for cortisol analysis using Cortisol-¹³C₃: A comprehensive validation study for an LC-MS/MS method to determine both free and total forms of urinary cortisol and its metabolites was conducted, demonstrating the utility of stable isotope-labeled standards like Cortisol-¹³C₃. This method is critical for precise quantitative analysis in clinical diagnostics and pharmaceutical research (Cuzzola, Mazzini, and Petri, 2014).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

51.8 °F - closed cup

Flash Point(C)

11.0 °C - closed cup


Certificates of Analysis (COA)

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Articles

This application note describes an accurate and sensitive, Supel™ Swift HLB DPX Tips based analysis of a total of 9 steroids (cortisone, cortisol, 11-deoxycortisol, androstenedione, testosterone, dehydroepiandrosterone, 5α-dihydrotestosterone, 17α-hydroxyprogesterone, and progesterone) in blood serum samples using two different standards (UTAK and NIST).

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