840038P

12:0 PS

1,2-dilauroyl-sn-glycero-3-phospho-L-serine (sodium salt), powder

• Synonym(s): 1,2-didodecanoyl-sn-glycero-3-phospho-L-serine (sodium salt); DLPS; PS(12:0/12:0)
• Empirical Formula (Hill Notation): C₃₀H₅₇NO₁₀PNa
• CAS Number: 208757-51-1
• Molecular Weight: 645.74
• UNSPSC Code: 51191904
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: powder
• packaging: pkg of 1 × 10 mg (840038P-10mg); pkg of 1 × 200 mg (840038P-200mg); pkg of 1 × 25 mg (840038P-25mg)
• manufacturer/tradename: Avanti Polar Lipids 840038P
• lipid type: phospholipids
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OC[C@](C([O-])=O)([H])[NH3+])=O)(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C30H58NO10P.Na/c1-3-5-7-9-11-13-15-17-19-21-28(32)38-23-26(24-39-42(36,37)40-25-27(31)30(34)35)41-29(33)22-20-18-16-14-12-10-8-6-4-2;/h26-27H,3-25,31H2,1-2H3,(H,34,35)(H,36,37);/q;+1/p-1/t26-,27+;/m1./s1
• InChI key: QBSSGICBQYAHPS-OUPRKWGVSA-M

Description

General description

Phosphatidylserine (PS), an aminophospholipid is negatively charged and accounts for 2–10% of total cellular lipid. It is located in the membrane leaflets.

Application

12:0 PS may be used:

• in the preparation of large unilamellar vesicles (LUVs)
• as a standard to spike replicas of extracted lipid droplets and calibration curve generation for lipidomic analysis
• to study its effects on α-secretase activity

Biochem/physiol Actions

Phosphatidylserine (PS) plays a key role in protein kinase C pathways. It also helps in confining the intracellular proteins to membrane leaflets of cytosol.

Packaging

5 mL Amber Glass Screw Cap Vial (840038P-10mg)

5 mL Amber Glass Screw Cap Vial (840038P-200mg)

5 mL Amber Glass Screw Cap Vial (840038P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Storage Class Code: 11 - Combustible Solids