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94829

Sigma-Aldrich

Poly(L-lactide)

average Mn 40,000

Synonym(s):

PLA, Poly(L-lactic acid)

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About This Item

Linear Formula:
CH3(CH2)15O(C6H8O4)nH
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

description

ester terminated

form

solid

mol wt

average Mn 40,000

degradation timeframe

>3 years

Application

medical device

Other Notes

end group: hexadecyl ester

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Articles

Interest in utilizing biodegradable polymers for biomedical applications has grown since the 1960s.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been widely explored for medical uses and are commercially available.

Immunosuppressive tumor-associated myeloid cells (TAMC) are responsible for glioblastoma (GBM) resistance to immunotherapies and existing standard of care treatments. This mini-review highlights recent progress in implementing nanotechnology in advancing TAMC-targeted therapies for GBM.

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