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928070

Sigma-Aldrich

Gold nanoparticles

10 nm diameter, alkyne functionalized, 1 ML, OD 50, in water

Synonym(s):

AuNP, GdNP, Gold NP

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About This Item

UNSPSC Code:
12141717
NACRES:
NA.22

Quality Level

100

description

Alkyne surface density: 1/nm2

concentration

in water

OD

50

core diam.

10 nm , coefficient of variance <12%

diameter

10 nm

λmax

520 nm

PDI

<0.200

functional group

alkyne

storage temp.

2-8°C

InChI

1S/Au

InChI key

PCHJSUWPFVWCPO-UHFFFAOYSA-N

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General description

Alkyne functionalized gold nanoparticles are suitable for covalent conjugation of any azide-tagged molecule through Cu(I)-catalyzed click chemistry. These goldnanoparticles allow for rapid generation of gold conjugates for subsequent use in downstream assays. Alkyne functionalized gold nanoparticles are more than 95% spherical and have uniform size distribution (CV <12%).

Application

Ideal for development of gold conjugates for use in applications such as blotting, lateral flow assays, microscopy, and transmission electron microscopy (TEM).

Storage and Stability

When stored for a long period of time gold nanoparticles may sediment at the bottom of the vial, which is especially prominent for larger particle sizes. Prior to use, re-suspend the sedimented particles by thorough mixing until a homogenous solution is obtained.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Wilson Luo et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 23(5), 1052-1059 (2016-10-12)
In this study, we report the design, synthesis, and characterization of small 3 nm water soluble gold nanoparticles (AuNPs) that feature cyclopropenone-masked strained alkyne moieties capable of undergoing interfacial strain-promoted cycloaddition (i-SPAAC) with azides after exposure to UV-A light. A strained

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