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925624

Sigma-Aldrich

Redox Responsive Poly(ethylene glycol)-block-poly(ε-caprolactone)

PEG average Mn 5,000, PCL Mn 15,000

Synonym(s):

Block copolymer, PEG-PCL with disulfide linkage, PEG-SS-PCL, Stimuli-responsive

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About This Item

Linear Formula:
CH3O(C2H4O)nC7H12O4S2(C6H10O2)
UNSPSC Code:
12352112
NACRES:
NA.23

form

solid (could be powder/granules/chunks)

Quality Level

mol wt

PCL Mn 15,000
PEG average Mn 5,000

color

white to beige, light yellow

storage temp.

2-8°C

Application

PEG-SS-PCL is a redox responsive, biocompatible, amphiphilic block copolymer composed of a hydrophilic poly(ethylene glycol) (PEG) block and a hydrophobic poly(ε-caprolactone) (PCL) block, with a reducible disulfide linkage between blocks. This polymer can be fabricated into Glutathione (GSH) responsive nanoparticles which can be used as an intracellular drug delivery system.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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