733857
DL-α-Tocopherol methoxypolyethylene glycol succinate solution
2 wt. % in H2O
Synonym(s):
Polyethylene glycol, TPGS-750-M
About This Item
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form
liquid
Quality Level
reaction suitability
reagent type: catalyst
reaction type: Bucherer Carbazole Synthesis
reagent type: surfactant
greener alternative product characteristics
Catalysis
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concentration
2 wt. % in H2O
refractive index
n20/D 1.336
density
1.002 g/mL at 25 °C
greener alternative category
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General description
Application
Included among the possible reactions are:
- Olefin metathesis
- Pd-catalyzed cross coupling reactions including Heck, Suzuki-Miyaura, Sonogashira and Buchwald-Hartwig reactions
- C-H activation reactions
Second generation amphiphile for cross-coupling reactions in water
Other Notes
From milligrams to kilograms: synthetic chemistry following nature′s lead
related product
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Articles
Lipshutz and co-workers have recently developed a second generation technology to their original PTS-enabling surfactant based on the polyoxyethanyl-α-tocopheryl succinate derivative, TPGS-750-M.
Prof. Bruce Lipshutz's labs developed surfactants for efficient water-based reactions, offering a greener alternative to solvent-based processes.
Protocols
TPGS-750-M, a second generation surfactant, may be used for Suzuki-Miyaura Reactions in Water at Room Temperature
Buchwald-Hartwig Amination Reaction in Water at Room Temperature using TPGS-750-M
Amide Coupling in a Box
TPGS-750-M, a second generation surfactant, may be used in water at room temperature for Buchwald-Hartwig Amination, Suzuki-Miyaura reactions, Heck reactions, Sonogashira reactions, Negishi reactions, and olefin metathesis.
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