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730270

Sigma-Aldrich

Poly(ethylene glycol) methyl ether acrylate

average Mn 2,000, acrylate, methoxy, MEHQ as inhibitor, chemical modification reagent polymerization reactions

Synonym(s):

Polyethylene glycol, Acryl-PEG, Methoxy PEG acrylate, Methoxy poly(ethylene glycol) monoacrylate, Poly(ethylene glycol) monomethyl ether monoacrylate, mPEG-acrylate

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About This Item

Linear Formula:
H2C=CHCO2(CH2CH2O)nCH3
CAS Number:
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23

product name

Poly(ethylene glycol) methyl ether acrylate, average Mn 2,000, contains MEHQ as inhibitor

form

solid

Quality Level

mol wt

average Mn 2,000

contains

MEHQ as inhibitor

reaction suitability

reagent type: chemical modification reagent
reaction type: Polymerization Reactions

transition temp

Tm 49-54 °C

density

1.09 g/mL at 25 °C (lit.)

Mw/Mn

<1.1

Ω-end

acrylate

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

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Preparation Note

Synthesized with an initial concentration of ≤1,500 ppm MEHQ

Storage Class Code

11 - Combustible Solids

WGK

WGK 3


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Articles

Accumulation of biological matter at surfaces is an inevitable event in virtually any environment in which natural and man-made materials are used. Although sometimes fouling of surfaces with biomolecules and bioorganisms has little consequence, biofouling must be minimized or controlled in order to maintain performance and safety of devices and structures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Devising biomaterial scaffolds that are capable of recapitulating critical aspects of the complex extracellular nature of living tissues in a threedimensional (3D) fashion is a challenging requirement in the field of tissue engineering and regenerative medicine.

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