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Sigma-Aldrich

Oxygen-18O2

99 atom % 18O, 99% (CP)

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About This Item

Linear Formula:
18O2
CAS Number:
32767-18-3
Molecular Weight:
36.00
MDL number:
MFCD00084251
UNSPSC Code:
12142200
PubChem Substance ID:
24881829
NACRES:
NA.12

vapor density

1.11 (vs air)

Quality Level

200

isotopic purity

99 atom % 18O

Assay

99% (CP)

form

gas

technique(s)

PET imaging: suitable

bp

−183 °C (lit.)

mp

−218 °C (lit.)

mass shift

M+4

SMILES string

[18O]=[18O]

InChI

1S/O2/c1-2/i1+2,2+2

InChI key

MYMOFIZGZYHOMD-XPULMUKRSA-N

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General description

Oxygen-18O2 is a naturally occurring stable isotope of oxygen. Natural abundance of 18O2 containing at least 99 atom % O-18.

Application

18O2 isotopic labelling was employed, in conjunction with time-of-flight secondary ion mass spectrometry, to characterize and elucidate the parts of the degradation mechanisms induced by molecular oxygen. Using 18O2 as a label, it is possible to study collagen degradation with this non-reutilized label and so avoid the large errors that are introduced by the recycling of other labels.
Oxygen-18O2 can be used to study the kinetic and functional analyses in photosynthesis research. It is used to estimate the role of oxygen in the vitamin-K dependent carboxylation reaction. Also used to measure the amount of oxygen produced by the etching a quartz tube with SF6 plasma.

Packaging

1 L quantity is packaged in a 450 mL carbon steel lecture bottle with brass CGA 110/180 valve. Nominal gas pressure at 21ºC is 20 psig for 1 L. This pressure is slightly above atmospheric pressure. Care must be taken when extracting this product from the cylinder.
All gas volumes are quoted at Standard Temperature and Pressure (STP) and not at Normal Temperature and Pressure (NTP). One STP Liter is 7.7% more gas than one NTP Liter.

Recommended products

Brass hose adapter Z146811 or brass body mini gas regulator Z513539 is recommended for 500 mL Sure/Pac cylinder (U.S only). For 1 L cylinder, either stainless steel control valve Z146951 or Z187224 is recommended.
PTFE sealing washers GCA inlet size 180 Z146994
PTFE sealing washers CGA inlet size 110 Z146986

hose barb

Product No.
Description
Pricing

Z146811

Hose adapter, brass

regulator

Product No.
Description
Pricing

Pictograms

Flame over circleGas cylinder
GHS03,GHS04

Signal Word

Danger

Hazard Statements

H270,H280

Hazard Classifications

Ox. Gas 1 - Press. Gas Compr. Gas

Storage Class Code

2A - Gases

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MBBD2612
MBBC8038
MBBC7207
MBBC6538
MBBC6305

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Catherine Fenselau et al.
Journal of proteome research, 8(5), 2140-2143 (2009-04-03)
Enzyme-catalyzed 18O2-labeling offers a universal strategy for uniform labeling of all peptides from any kind of proteins, including post-translationally modified proteins. It is applicable to clinical samples with unrivaled sensitivity. This review discusses strengths and limitations, and advocates the separation
J A Molnar et al.
The Biochemical journal, 250(1), 71-76 (1988-02-15)
To explore the effects of growth retardation, caused by restricted protein intake, on collagen turnover in the whole skin, Sprague-Dawley rats (n = 20) were labelled with 18O2 and fed on either an adequate (18%) or a low (3%) lactalbumin
Dmitriy Shevela et al.
Frontiers in plant science, 4, 473-473 (2013-12-11)
Monitoring isotopic compositions of gaseous products (e.g., H2, O2, and CO2) by time-resolved isotope-ratio membrane-inlet mass spectrometry (TR-IR-MIMS) is widely used for kinetic and functional analyses in photosynthesis research. In particular, in combination with isotopic labeling, TR-MIMS became an essential
Sui So et al.
Physical chemistry chemical physics : PCCP, 16(45), 24954-24964 (2014-10-18)
β-Hydroxyperoxyl radicals are formed during atmospheric oxidation of unsaturated volatile organic compounds such as isoprene. They are intermediates in the combustion of alcohols. In these environments the unimolecular isomerization and decomposition of β-hydroxyperoxyl radicals may be of importance, either through

Related Content

Stable Isotopes in PET (Positron Emission Tomography)

Labeled isotopes used as target materials in imaging have provided insights into the various mechanisms of human physiology and have lead to treatments for diseases. Water-18O is used for the production of 18F radionuclides, such as 18FDG (Fluoro-deoxyglucose). 18FDG used in PET and with other imaging technologies, such as CT/SPECT, has led to the diagnosis and treatment of a wide range of diseases, including lung, liver, and brain tumors, epilepsy, and Alzheimer’s.

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