594539

4-Methoxycarbonylphenylboronic acid

≥95%

• Synonym(s): (4-Carbomethoxyphenyl)boronic acid, 4-Carbomethoxybenzeneboronic acid, 4-Methoxycarbonylbenzeneboronic acid, 4-borono-benzoic acid 1-methyl ester, p-(Methoxycarbonyl)boronic acid, p-(Methoxycarbonyl)phenylboronic acid, p-borono-benzoic acid methyl ester, Methyl 4-boronobenzoate, Methyl p-boronobenzoate
• Empirical Formula (Hill Notation): C₈H₉BO₄
• CAS Number: 99768-12-4
• Molecular Weight: 179.97
• MDL number: MFCD01632203
• UNSPSC Code: 12352103
• PubChem Substance ID: 24881520
• NACRES: NA.22

Properties

• Quality Level: 100
• Assay: ≥95%
• form: powder
• mp: 197-200 °C (lit.)
• functional group: ester
• SMILES string: COC(=O)c1ccc(cc1)B(O)O
• InChI: 1S/C8H9BO4/c1-13-8(10)6-2-4-7(5-3-6)9(11)12/h2-5,11-12H,1H3
• InChI key: PQCXFUXRTRESBD-UHFFFAOYSA-N

Description

Application

Reagent used for

• Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence
• Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides
• One-pot ipso-nitration of arylboronic acids
• Copper-catalyzed nitration
• Cyclocondensation followed by palladium-phosphine-catalyzed Suzuki-Miyaura coupling

• Reagent used in Preparation of
• Biaryls via nickel-catalyzed Suzuki-Miyaura cross-coupling reaction of aryl halides with arylboronic acid†
• Chromenones and their bradykinin B1 antagonistic activit†
• Pt nanoparticles@Photoactive metal-organic frameworks resulting in efficient hydrogen evolution via synergistic photoexcitation and electron injectio†
• Salicylate-based thienylbenzoic acids as E. coli methionine aminopeptidase inhibitor†

Other Notes

Contains varying amount of anhydride

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves