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308102

Sigma-Aldrich

N,N-Dimethylhexylamine

98%

Synonym(s):

1-(Dimethylamino)hexane, N,N-Dimethyl-1-hexanamine, N,N-Dimethyl-n-hexylamine, N,N-Dimethylhexylamine, N-Hexyldimethylamine

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About This Item

Linear Formula:
CH3(CH2)4CH2N(CH3)2
CAS Number:
4385-04-0
Molecular Weight:
129.24
Beilstein:
1732757
EC Number:
224-491-8
MDL number:
MFCD00009522
UNSPSC Code:
12352100
PubChem Substance ID:
24858648
NACRES:
NA.22

Assay

98%

form

liquid

refractive index

n20/D 1.414 (lit.)

bp

146-150 °C (lit.)

density

0.744 g/mL at 25 °C (lit.)

SMILES string

CCCCCCN(C)C

InChI

1S/C8H19N/c1-4-5-6-7-8-9(2)3/h4-8H2,1-3H3

InChI key

QMHNQZGXPNCMCO-UHFFFAOYSA-N

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General description

The free Salinomycin (Sali), that has selective toxicity to cancer stem cells (CSCs), was encapsulated into the nanoparticle along with the additive N,N-dimethylhexylamine.

Application

N,N-Dimethylhexylamine was used as ion-pairing agent to study the problem of poor retention of uridine diphosphate-linked intermediates on reverse phase media. It was also used in the determining the five monophosphate nucleotides (cytidine 5′-monophosphate, uridine 5′-monophosphate, adenosine 5′-monophosphate, inosine 5′-monophosphate and guanosine 5′-monophosphate) in baby foods.

Pictograms

FlameCorrosion
GHS02,GHS05

Signal Word

Danger

Hazard Statements

H226,H314

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

93.2 °F - closed cup

Flash Point(C)

34 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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N,N-Dimethylethylamine ≥99%

Sigma-Aldrich

652571

N,N-Dimethylethylamine

Pilar Viñas et al.
Journal of chromatography. A, 1217(32), 5197-5203 (2010-06-29)
A liquid chromatography with diode array detection coupled to dual electrospray atmospheric pressure chemical ionization time-of-flight mass spectrometry (HPLC/ESI-APCI-TOF-MS) method is described for the rapid determination of five monophosphate nucleotides (cytidine 5'-monophosphate, uridine 5'-monophosphate, adenosine 5'-monophosphate, inosine 5'-monophosphate and guanosine
Harika Vemula et al.
Analytical biochemistry, 465, 12-19 (2014-08-03)
Bacterial cell wall biosynthesis is the target of several antibiotics and is of interest as a target for new inhibitor development. The cytoplasmic steps of this pathway involve a series of uridine diphosphate (UDP)-linked peptidoglycan intermediates. Quantification of these intermediates
Peng Zhao et al.
Molecular pharmaceutics, 11(8), 2703-2712 (2014-06-25)
Salinomycin (Sali) has selective toxicity to cancer stem cells (CSCs), a subpopulation of cancer cells that have been recently linked with tumor multidrug resistance (MDR). To utilize its selective toxicity for cancer therapy, we sought to devise a nanoparticle (NP)

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