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228559

Sigma-Aldrich

3-Phosphonopropionic acid

technical grade, 94%

Synonym(s):

2-Carboxyethanephosphonic acid

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About This Item

Linear Formula:
(HO)2P(O)CH2CH2COOH
CAS Number:
5962-42-5
Molecular Weight:
154.06
EC Number:
227-738-8
MDL number:
MFCD00002770
UNSPSC Code:
12352100
PubChem Substance ID:
24853694
NACRES:
NA.22

grade

technical grade

Assay

94%

form

solid

SMILES string

OC(=O)CCP(O)(O)=O

InChI

1S/C3H7O5P/c4-3(5)1-2-9(6,7)8/h1-2H2,(H,4,5)(H2,6,7,8)

InChI key

NLBSQHGCGGFVJW-UHFFFAOYSA-N

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Application

3-Phosphonopropionic acid was used to functionalize the bulk phosphate glass surface.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point(F)

302.0 °F - closed cup

Flash Point(C)

150 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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H T Schmidt et al.
Journal of microencapsulation, 23(7), 769-781 (2006-11-25)
Hollow calcium phosphate nanoparticles capable of encapsulating poorly water-soluble molecules were produced by self-assembly. Previously reported were solid calcium phosphate nanoparticles and water-filled calcium phosphate nanocapsules suited for encapsulating mostly hydrophilic, but not hydrophobic compounds. Here, calcium phosphate was deposited
Charles E McKenna et al.
Journal of medicinal chemistry, 53(9), 3454-3464 (2010-04-17)
3-(3-Pyridyl)-2-hydroxy-2-phosphonopropanoic acid (3-PEHPC, 1) is a phosphonocarboxylate (PC) analogue of 2-(3-pyridyl)-1-hydroxyethylidenebis(phosphonic acid) (risedronic acid, 2), an osteoporosis drug that decreases bone resorption by inhibiting farnesyl pyrophosphate synthase (FPPS) in osteoclasts, preventing protein prenylation. 1 has lower bone affinity than 2
Serena Donnini et al.
Proteins, 76(1), 138-150 (2008-12-18)
When estimating binding affinities of a ligand, which can exists in multiple forms, for a target molecule, one must consider all possible competing equilibria. Here, a method is presented that estimates the contribution of the protonation equilibria of a ligand
Satya Narayan Patel et al.
Bioresource technology, 247, 633-639 (2017-10-11)
The aim of the study was to covalently immobilize Smt3-D-psicose 3-epimerase onto functionalized iron oxide magnetic nanoparticles. After immobilization, K
Vishal Singh et al.
International journal of biological macromolecules, 115, 590-599 (2018-04-24)
Magnetite and magnetite core/shell (Fe3O4/SiO2) nanoparticles were synthesized and functionalized with two different alkyl chain length linkers that were 3-Phosphonopropionic acid (3-PPA) and 16-Phosphonohexadecanoic acid (16-PHDA). Xylanase (EC 3.2.1.8, endo-1,4-xylanase, endo-1), was immobilized on as synthesized bare and silica coated
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