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Key Documents

189758

Sigma-Aldrich

3-Nitrobenzamide

98%

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About This Item

Linear Formula:
O2NC6H4CONH2
CAS Number:
Molecular Weight:
166.13
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

98%

form

solid

mp

140-143 °C (lit.)

functional group

amide
nitro

SMILES string

NC(=O)c1cccc(c1)[N+]([O-])=O

InChI

1S/C7H6N2O3/c8-7(10)5-2-1-3-6(4-5)9(11)12/h1-4H,(H2,8,10)

InChI key

KWAYEPXDGHYGRW-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Y Uchigata et al.
The Journal of biological chemistry, 257(11), 6084-6088 (1982-06-10)
We have shown previously that alloxan and streptozotocin, two major diabetogenic agents, cause DNA strand breaks in rat pancreatic islets and stimulate nuclear poly(ADP-ribose) synthetase, thereby depleting intracellular NAD level and inhibiting proinsulin synthesis (Okamoto, H. (1981) Mol. Cell. Biochem.
M R Purnell et al.
The Biochemical journal, 185(3), 775-777 (1980-03-01)
In a search for new inhibitors of the nuclear enzyme poly(ADP-ribose) synthetase, it was found that various benzamides substituted in the 3-position were the most inhibitory compounds found to date. Two of the benzamides, 3-aminobenzamide and 3-methoxybenzamide, were found to

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