PHL82571

Isosilybin B

phyproof^® Reference Substance

• Synonym(e): (2R,3R)-3,5,7-Trihydroxy-2-[(2S,3S)-2-(4-hydroxy-3-methoxy-phenyl)-3-(hydroxymethyl)-2,3-dihydro-benzo[1,4]dioxin-6-yl]-4-chromanon
• Empirische Formel (Hill-System): C₂₅H₂₂O₁₀
• CAS-Nummer: 142796-22-3
• Molekulargewicht: 482.44
• MDL-Nummer: MFCD18783097
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: primary reference standard
• Produktlinie: phyproof^® Reference Substance
• Assay: ≥80.0% (HPLC)
• Form: solid
• Hersteller/Markenname: PhytoLab
• SMILES String: COc1cc(ccc1O)[C@@H]2Oc3ccc(cc3O[C@H]2CO)[C@H]4Oc5cc(O)cc(O)c5C(=O)[C@@H]4O
• InChI: 1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-18-7-12(3-5-16(18)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25+/m0/s1
• InChIKey: FDQAOULAVFHKBX-WAABAYLZSA-N

Beschreibung

Allgemeine Beschreibung

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Anwendung

• Isosilybin B for hepatoprotective studies: Research elucidates how Isosilybin B regulates lipogenesis and fatty acid oxidation through the AMPK/SREBP-1c/PPARα pathway, offering insights into its potential as a hepatoprotective compound and its application in liver health studies (Liu et al., 2022).


• Isosilybin B in anticancer research: The study discusses the development of a topical formulation containing silymarin complex, including Isosilybin B, highlighting its skin permeability and potential in cancer prevention through dermal application (Shankar et al., 2023).


• Isosilybin B in antioxidant research: A study explores the antiviral efficacy of natural phytochemicals including Isosilybin B against the SARS-CoV-2 spike glycoprotein, emphasizing its role in antioxidant biochemistry and potential therapeutic applications (Aloufi et al., 2022).

Sonstige Hinweise

This compound is commonly found in plants of the genus: silybum

Rechtliche Hinweise

phyproof is a registered trademark of PhytoLab GmbH & Co. KG

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable