G005738

HPLC Analysis of Cosmetic Preservatives on Ascentis^® Express RP-Amide

application for HPLC

Eigenschaften

• Methode(n): HPLC: suitable
• Testparameter: column: Ascentis Express RP-Amide, 10 cm x 3 mm I.D., 2.7 μm particles (53918-U); mobile phase: [A] water; [B] methanol; (60:40, A:B); flow rate: 0.6 mL/min; pressure: 2900 psi (200 bar); column temp.: 50 °C; detector: UV, 250 nm; injection: 1 μL; sample: methyl-, benzylparaben (50 mg/L), ethylparaben (30 mg/L), propyl-, butylparaben (100 mg/L), 2-phenoxyethanol (1.5 g/L),1-phenoxy-2-propanol (3 g/L), all in 40% methanol
• Eignung: application for HPLC
• Anwendung(en): cleaning products; cosmetics; personal care

Beschreibung

Hinweis zur Analyse

With the publication Borremans, M. et.al. 2004, Chromatographia 59: 47-53 as a reference, this method is 10% faster, but with superior resolution of critical pairs; in this case, the minimum USP resolution is 2.4.

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyt

Ethylene glycol monophenyl ether
1-Phenoxy-2-propanol
Methyl 4-hydroxybenzoate
Ethyl 4-hydroxybenzoate
Butylparaben
Benzyl 4-hydroxybenzoate