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Astec® Cyclobond™ I 2000 HP-RSP Chiral HPLC Column

5 μm particle size, L × I.D. 25 cm × 4.6 mm

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About This Item

UNSPSC-Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52

Materialien

stainless steel column

Qualitätsniveau

100

Produktlinie

Astec®

Verpackung

pkg of 1 ea

Hersteller/Markenname

Astec®

Parameter

0-50 °C temperature
172 bar pressure (2500 psi)

Methode(n)

HPLC: suitable
LC/MS: suitable

L × ID

25 cm × 4.6 mm

Matrix

silica particle platform
fully porous particle

Aktive Matrixgruppe

cyclodextrin, beta- phase

Partikelgröße

5 μm

Porengröße

100 Å

Betriebs-pH-Wert

3.5-7

Trenntechnik

chiral

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Allgemeine Beschreibung

In the design of this new chemistry, it was an objective to create a very stable and reproducible phase with shorter retention times, while maintaining or improving selectivity over CYCLOBOND I 2000 RSP. With that goal and more achieved, CYCLOBOND I 2000 HP-RSP separates by extended H-bonding capability, and offers broad chiral selectivity for chiral screening. It is most beneficial for basic and neutral compounds.

  • Bonded phase: (R,S)-Hydroxypropyl modified β-cyclodextrin (high performance)

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Rechtliche Hinweise

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
281392-04
281392-03
281392-02
281392-01
281383-04

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Indirect photodetection of pregnanolone on a Cyclobond column by high-performance liquid chromatography
Agnus, Benoit, et al.
Journal of Chromatography A, 633 (1), 27-33 (1994)
Rapid high-performance liquid chromatographic separation of barley malt a-amylase on cyclobond columns
Henson, Cynthia A., Stone, Julie M.
Journal of Chromatography A, 469, 361-367 (1989)
Assessment of the complexation degree of camptothecin derivatives and cyclodextrins using spectroscopic and separative methodologies
Foulon, C., et al.
Tetrahedron Asymmetry, 20 (21), 2482-2489 (2009)
Reprint of: Enantiomeric separation of functionalized ethano-bridged Troger bases using macrocyclic cyclofructan and cyclodextrin chiral selectors in high-performance liquid chromatography and capillary electrophoresis with application of principal component analysis
Weatherly, Choyce A., et al.
Journal of Chromatography. B, Biomedical Applications, 968, 40-48 (2014)
Roland Török et al.
Journal of chromatography. A, 1098(1-2), 75-81 (2005-11-30)
Direct high-performance liquid chromatographic methods were developed for the enantioseparation of (R,S)-bicalutamide (1) and its analogs (+/-)-3-chloro-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (2), (+/-)-N-(4-cyano-3-(trifluoro-methyl)phenyl)-2-methyloxirane-2-carboxamide (3), (+/-)-4-fluorophenylsulfonyl-2-hydroxy-2-methylpropionic acid (4) and (+/-)-3-hydroxy-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide (5). The methods involved the use of a cellulose-based Chiralcel OD-H, macrocyclic glycopeptide-based Chirobiotic T
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Verwandter Inhalt

Astec CYCLOBOND™

CYCLOBOND is the name given to Astec technology for bonding cyclodextrins to a high purity silica gel through a stable ether linkage.

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.