T6704

Tandospirone

≥98% (HPLC)

• Synonym(e): (1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt, SM 3997
• Empirische Formel (Hill-System): C₂₁H₂₉N₅O₂
• CAS-Nummer: 87760-53-0
• Molekulargewicht: 383.49
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329826853
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Lagerbedingungen: protect from light
• Löslichkeit: DMSO: 38 mg/mL
• Ersteller: Dainippon Sumitomo
• Lagertemp.: 2-8°C
• SMILES String: O=C1[C@@H]2[C@H]3CC[C@H](C3)[C@@H]2C(=O)N1CCCCN4CCN(CC4)c5ncccn5
• InChI: 1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-
• InChIKey: CEIJFEGBUDEYSX-FZDBZEDMSA-N

Beschreibung

Biochem./physiol. Wirkung

Tandospirone is a partial agonist at 5HT_1A receptors. It significantly reduces haloperidol-induced bradykinesia in a dose-dependent manner. The potency of tandospirone is equal to that of buspirone and approximate half that of diazepam. The potency of tandospirone as a dopamine antagonistic is less than 1/4 that of buspirone.

Leistungsmerkmale und Vorteile

This compound was developed by Dainippon Sumitomo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable