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Merck

T1539

Sigma-Aldrich

(+)-α-Tocopherol

Type VI, from vegetable oil, liquid (≥0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, ≥1000 IU/g

Synonym(e):

2,5,7,8-Tetramethyl-2-(4′,8′,12′-trimethyltridecyl)-6-chromanol, 5,7,8-Trimethyltocol, Vitamin E

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About This Item

Empirische Formel (Hill-System):
C29H50O2
CAS-Nummer:
Molekulargewicht:
430.71
Beilstein:
4712525
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352205
eCl@ss:
34058016
PubChem Substanz-ID:
NACRES:
NA.75

Biologische Quelle

vegetable oil

Typ

Type VI

Produktlinie

BioReagent

Form

liquid (≥0.88M based on potency, density and molecular wt.)

Wirksamkeit

≥600 mg d-α-tocopherol per g

Spezifische Aktivität

≥1000 IU/g

Mol-Gew.

Mw 430.71 g/mol

Konzentration

≥600 mg/g

Methode(n)

cell culture | insect: suitable

Farbe

yellow-orange

Brechungsindex

n20/D 1.505 (lit.)

bp

200-220 °C/0.1 mmHg (lit.)

Löslichkeit

chloroform: soluble 0.1 mL/mL, clear, faintly yellow to yellow

Dichte

0.95 g/mL at 25 °C (lit.)

Format

neat

Lagertemp.

2-8°C

SMILES String

CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@]1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3/t21-,22-,29-/m1/s1

InChIKey

GVJHHUAWPYXKBD-IEOSBIPESA-N

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Anwendung

Use in insect cell culture applications as an antioxidant.

Sonstige Hinweise

Mixed constitutional (α, β, γ, δ) isomers.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

230.0 °F - closed cup

Flammpunkt (°C)

110 °C - closed cup

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Die Dokumentenbibliothek aufrufen

Y Loetscher et al.
Poultry science, 92(11), 2938-2948 (2013-10-19)
Prevention of lipid oxidation needs special attention because a high proportion of fatty acids in broiler meat are unsaturated. A feeding experiment was conducted to evaluate the antioxidant effect of dietary addition of rosemary, chokeberry pomace, rosehip, or nettle in
Karl Michaëlsson et al.
The American journal of clinical nutrition, 99(1), 107-114 (2013-11-15)
A reduction in the formation of free radicals and oxidative stress might reduce the rate of bone loss and muscle wasting. The objective was to determine whether α-tocopherol intake or serum concentrations are associated with fracture risk in older women
Jen-Hao Cheng et al.
European journal of medicinal chemistry, 46(4), 1222-1231 (2011-02-25)
In an effort to develop novel antioxidant as anticancer agents, a series of xanthones were prepared. In vitro screening, the synthetic xanthones revealed significant inhibitory effects on xanthine oxidase and ABTS radical-cation scavenging activity. The selective compounds 2 and 8
Ying Yang et al.
Food chemistry, 141(1), 473-481 (2013-06-19)
Vitamin E is an essential micronutrient for humans and animals due to its antioxidant and non-antioxidant biological activities. The α-tocopherol acetate form is often used in foods and other products due to its high biological activity and chemical stability. In
Laura L Baxter et al.
Nutrients, 4(6), 467-490 (2012-07-24)
Vitamin E isoforms are essential nutrients that are widely used as dietary supplements and therapeutic agents for a variety of diseases. However, their pharmacokinetic (PK) properties remain poorly characterized, and high dosage animal studies may provide further information on their

Artikel

Importance and uses of vitamin E (tocopherol) in serum-free eukaryotic, including hybridoma and chinese hamster ovary (CHO), cell cultures.

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

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