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SRP6238

Sigma-Aldrich

TRAIL murine

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Synonym(e):

Apo2 Ligand, TL2, TNF-related apoptosis-inducing Ligand, TNFSF10

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About This Item

UNSPSC-Code:
12352200
NACRES:
NA.32

Biologische Quelle

rat

Rekombinant

expressed in E. coli

Assay

≥95% (SDS-PAGE)

Form

lyophilized powder

Mol-Gew.

20 kDa

Verpackung

pkg of 10 μg
pkg of 50 μg

Verunreinigungen

<1 EU/μg endotoxin (LAL test)

UniProt-Hinterlegungsnummer

P50592

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

mouse ... TRAIL(22035)

Allgemeine Beschreibung

TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell′s apoptotic machinery. Recombinant murine TRAIL is a 174 amino acid polypeptide (20.0 kDa), consisting of the TNF homologous portion of the extracellular domain of the full length TRAIL protein.

Physikalische Form

Sterile filtered through a 0.2 micron filter. Lyophilized from 10 mM Sodium Phosphate, pH 7.0.

Rekonstituierung

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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