SRP4908

Visfatin

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), ≥95% (HPLC)

• Synonym(e): Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog
• UNSPSC-Code: 12352200

Eigenschaften

• Biologische Quelle: mouse
• Rekombinant: expressed in E. coli
• Assay: ≥95% (HPLC); ≥95% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: ~55.0 kDa
• Verpackung: pkg of 10 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Verunreinigungen: endotoxin, tested
• NCBI-Hinterlegungsnummer: Q99KQ4
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Nampt(59027)

Beschreibung

Allgemeine Beschreibung

Visfatin is also called pre-B cell colony enhancing factor, nicotinamide phosphoribosyltransferase, pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt and PBEF. Visfatin is an adipocytokine produced by visceral fat.

Biochem./physiol. Wirkung

Visfatin has a role in mammalian nicotinamide adenine dinucleotide (NAD⁺) biosynthesis. Studies have shown that mice deficient in visfatin in the forebrain excitatory neurons show hyperactivity, diminished anxiety-like behaviors and impaired learning and memory. It has also been shown that visfatin stimulates glucose uptake and adenosine monophosphate-activated protein kinase (AMPK) phosphorylation in mouse C2C12 skeletal muscle cells.

Physikalische Form

Lyophilized without any additives.

Rekonstituierung

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in PBS to the concentration of 0.1-1 mg/mL.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable