SRP3246

IP-10 from rat

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

• Synonym(e): CXCL10, crg-2, g-Interferon Inducible Protein 10
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: rat
• Rekombinant: expressed in E. coli
• Assay: ≥98% (HPLC); ≥98% (SDS-PAGE)
• Form: lyophilized
• Mol-Gew.: 8.6 kDa
• Verpackung: pkg of 25 μg
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: <0.2 EU/μg endotoxin, tested
• Farbe: off-white to yellow
• UniProt-Hinterlegungsnummer: P48973
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: rat ... CXCL10(245920)

Beschreibung

Allgemeine Beschreibung

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.

Biochem./physiol. Wirkung

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. Recombinant rat IP-10 is an 8.6 kDa protein containing 77 amino acid residues, including the four conserved cysteine residues present in CXC chemokines.

Sequenz

IPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP

Physikalische Form

Lyophilized with no additives.

Rekonstituierung

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1