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Key Documents

SRP2025

Sigma-Aldrich

p52 human

recombinant, expressed in E. coli, ≥70% (SDS-PAGE)

Synonym(e):

DFS70, LEDGF, MGC74712, PAIP, p52

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About This Item

UNSPSC-Code:
12352202
NACRES:
NA.26

Biologische Quelle

human

Rekombinant

expressed in E. coli

Assay

≥70% (SDS-PAGE)

Form

frozen liquid

Mol-Gew.

~39 kDa

Verpackung

pkg of 10 μg

Konzentration

600 μg/mL

Farbe

clear colorless

NCBI-Hinterlegungsnummer

NM_021144

UniProt-Hinterlegungsnummer

O75475

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... PSIP1(11168)

Biochem./physiol. Wirkung

The human p52 protein is a non-TAF transcription coactivator that mediates activator-dependent transcription by RNA polymerase II. The function of p52 is through interactions with transcriptional activators and the basal transcription machinery. In addition, p52 may also interact with several cellular proteins including the transcription coactivator PC4, the essential splicing factor ASF/SF2 and the nuclear protein nucleolin.

Physikalische Form

Clear and colorless frozen liquid solution

Angaben zur Herstellung

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. While working, please keep sample on ice.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

H Ge
Nucleic acids research, 28(2), e3-e3 (1999-12-22)
Protein-protein interactions have been widely used to study gene expression pathways and may be considered as a new approach to drug discovery. Here I report the development of a universal protein array (UPA) system that provides a sensitive, quantitative, multi-purpose
H Ge et al.
Molecular cell, 2(6), 751-759 (1999-01-14)
Increasing evidence suggests that pre-mRNA splicing can take place cotranscriptionally in vivo. However, insight into how these two processes are linked has been lacking. Here, we describe that a novel transcriptional coactivator, p52, interacts not only with transcriptional activators and
H Ge et al.
The EMBO journal, 17(22), 6723-6729 (1998-11-21)
Transcriptional activation in human cell-free systems containing RNA polymerase II and general initiation factors requires the action of one or more additional coactivators. Here, we report the isolation of cDNAs encoding two novel human transcriptional coactivators (p52 and p75) that

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