SML3208

CPYPP

≥98% (HPLC)

• Synonym(e): 4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
• Empirische Formel (Hill-System): C₁₈H₁₃ClN₂O₂
• CAS-Nummer: 310460-39-0
• Molekulargewicht: 324.76
• MDL-Nummer: MFCD00980987
• UNSPSC-Code: 51111800
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: orange to dark red
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: −20°C
• SMILES String: Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
• InChI: 1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)

Beschreibung

Biochem./physiol. Wirkung

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids