SML3021

ADLumin-1

≥98% (HPLC)

• Synonym(e): 6-((1E,3E)-4-(4-(dimethylamino)phenyl)buta-1,3-dien-1-yl)-2-methylimidazo[1,2-a]pyrazin-3(7H)-one, 6-[4-[4-(Dimethylamino)phenyl]-1,3-butadien-1-yl]-2-methyl-imidazo[1,2-a]pyrazin-3(7H)-one
• Empirische Formel (Hill-System): C₁₉H₂₀N₄O
• CAS-Nummer: 2417555-90-7
• Molekulargewicht: 320.39
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: faint yellow to dark orange
• Löslichkeit: H₂O: 0.1 mg/mL (warmed)
• Lagertemp.: 2-8°C
• SMILES String: CN(C1=CC=C(C=C1)/C=C/C=C/C2=CN3C(N=C(C3=O)C)=CN2)C

Beschreibung

Biochem./physiol. Wirkung

ADLumin-1 brain blood barrier penetrant smart chemiluminescence probe for Aβ (amyloid beta) species. Upon binding to Aβ, ADLumin-1 chemiluminescence dramatically increases and its peak shifts from 590 nm to 540 nm. ADLumin-1 is suitable for in vivo dually-amplify signal via chemiluminescence resonance energy transfer (DAS-CRET) with CRANAD-3 a smart NIRF (near infrared fluorescence imaging) probe for Aβs. Apparently both probes bind to Aβ aggregates in close proximity.

brain blood barrier penetrant smart chemiluminescence probe for Aβ (amyloid beta) species

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable