SML2999

KL201

≥97% (HPLC)

• Synonym(e): 2-Bromo-N-(5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl)-benzamide
• Empirische Formel (Hill-System): C₁₇H₁₄BrN₃OS
• CAS-Nummer: 302939-48-6
• Molekulargewicht: 388.28
• UNSPSC-Code: 12352200

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥97% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C(C1=CC=CC=C1Br)NC2=NC=NC3=C2C4=C(CCCC4)S3

Beschreibung

Biochem./physiol. Wirkung

KL201 is a circadian clock modulator that lengthens a circadian period in cells and tissues. KL201 selectively regulate cryptochrome 1 (Cry1). It binds to FAD-binding pocket of CRY1 preventing interaction with FBXL3 and ubiquitin-dependent degradation.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable