SML2751

UCSF7447

≥98% (HPLC)

• Synonym(e): 2-Bromo-4-chloro-N-[3-(1H-1,2,4-triazol-5-yl)phenyl]-benzenemethanamine, ZINC555417447
• Empirische Formel (Hill-System): C₁₅H₁₂BrClN₄
• CAS-Nummer: 2305480-97-9
• Molekulargewicht: 363.64
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: Brc1c(ccc(c1)Cl)CNc2cc(ccc2)c3[nH]ncn3
• InChI: 1S/C15H12BrClN4/c16-14-7-12(17)5-4-11(14)8-18-13-3-1-2-10(6-13)15-19-9-20-21-15/h1-7,9,18H,8H2,(H,19,20,21)
• InChIKey: QPTCYEYTAWEZNT-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

UCSF7447 (ZINC555417447) brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor, which decelerates re-entrainment in mouse model of east-bound jetlag. Unexpectedly UCSF7447 advances the phase of the mouse circadian clock when administer at dusk.

brain permeable, potent and selective inverse agonist of both human and mouse melatonin MT1 receptor

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable