SML2351

Dabigatran etexilate

≥98% (HPLC)

• Synonym(e): N-[[2-[[[4-[[[(Hexyloxy)carbonyl]amino]iminomethyl] phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine ethyl ester
• Empirische Formel (Hill-System): C₃₄H₄₁N₇O₅
• CAS-Nummer: 211915-06-9
• Molekulargewicht: 627.73
• MDL-Nummer: MFCD22422841
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: O=C(OCCCCCC)NC(C(C=C1)=CC=C1NCC2=NC3=CC(C(N(CCC(OCC)=O)C4=NC=CC=C4)=O)=CC=C3N2C)=N
• InChI: 1S/C34H41N7O5/c1-4-6-7-10-21-46-34(44)39-32(35)24-12-15-26(16-13-24)37-23-30-38-27-22-25(14-17-28(27)40(30)3)33(43)41(20-18-31(42)45-5-2)29-11-8-9-19-36-29/h8-9,11-17,19,22,37H,4-7,10,18,20-21,23H2,1-3H3,(H2,35,39,44)
• InChIKey: KSGXQBZTULBEEQ-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Dabigatran etexilate is a prodrug of dabigatran, a nonpeptide direct thrombin inhibitor. Dabigatron is an anticoagulant that functions by directly inhibiting both free and fibrin-bound thrombin. Dabigatron has been shown to prevent strokes in those with atrial fibrillation not caused by heart valve issues.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable