SML2087

SJ000291942

≥98% (HPLC)

• Synonym(e): 2-(4-Ethylphenoxy)-N-(4-fluoro-3-nitrophenyl)-acetamide
• Empirische Formel (Hill-System): C₁₆H₁₅FN₂O₄
• CAS-Nummer: 425613-09-8
• Molekulargewicht: 318.30
• MDL-Nummer: MFCD02219567
• UNSPSC-Code: 12352202
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 2 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: CCC1=CC=C(OCC(NC2=CC([N+]([O-])=O)=C(F)C=C2)=O)C=C1

Beschreibung

Biochem./physiol. Wirkung

SJ000291942 is an activator of Bone Morphogenetic Protein (BMP) signaling with an EC50 value < 1 μM. Bone Morphogenetic Proteins (BMPs) are a group of growth factors and cytokines were originally discovered by their ability to induce the formation of bone and cartilage, but are now considered to constitute a group of pivotal morphogenetic signals, orchestrating tissue architecture throughout the body. SJ000291942 was shown to ventralize zebrafish embryos, activate SMAD1/5/8 phosphorylation, and induce the differentiation of C2C12 myoblasts to osteoblasts in manner consistent with BMP4 activation.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3