SML1274

RI-1

≥98% (HPLC)

• Synonym(e): 3-Chloro-1-(3,4-dichlorophenyl)-4-(4-morpholinyl)-1H-pyrrole-2,5-dione
• Empirische Formel (Hill-System): C₁₄H₁₁Cl₃N₂O₃
• CAS-Nummer: 415713-60-9
• Molekulargewicht: 361.61
• MDL-Nummer: MFCD00814248
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825761
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: yellow to orange
• Löslichkeit: DMSO: 10 mg/mL, clear
• Lagertemp.: 2-8°C
• SMILES String: ClC1=C(Cl)C=CC(N2C(C(N3CCOCC3)=C(Cl)C2=O)=O)=C1
• InChI: 1S/C14H11Cl3N2O3/c15-9-2-1-8(7-10(9)16)19-13(20)11(17)12(14(19)21)18-3-5-22-6-4-18/h1-2,7H,3-6H2
• InChIKey: MWSUIZKGNWELRF-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

RI-1 is a cell-permeable RAD51 inhibitor that binds covalently to the protein surface at Cysteine 319. RI-1 disrupts homologous recombination in human cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable