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Merck

SML0688

Sigma-Aldrich

PO1

≥98% (HPLC)

Synonym(e):

2′,3′,6′,7′-Tetrahydro-12′-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-Spiro[isobenzofuran-1(3H)

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About This Item

Empirische Formel (Hill-System):
C32H32BNO5
CAS-Nummer:
Molekulargewicht:
521.41
UNSPSC-Code:
12352200
NACRES:
NA.77

Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Farbe

faintly pink to red

Löslichkeit

DMSO: 1 mg/mL, clear (warmed)

Lagertemp.

2-8°C

InChI

1S/C32H32BNO5/c1-30(2)31(3,4)39-33(38-30)20-13-14-24-26(18-20)36-28-22-11-8-16-34-15-7-9-19(27(22)34)17-25(28)32(24)23-12-6-5-10-21(23)29(35)37-32/h5-6,10,12-14,17-18H,7-9,11,15-16H2,1-4H3

InChIKey

KNTNXZHHCPNNGB-UHFFFAOYSA-N

Allgemeine Beschreibung

Peroxy orange 1 (PO1) is a H2O2-specific fluorescent probe. PO1 probe is non-trappable and highly permeable in nature.

Anwendung

Peroxy orange 1 (PO1) has been used to detect H2O2 in RtSS (root to shoot silencing) and wild-type Columbia and in rci3-1 and rci3-2 mutants.

Biochem./physiol. Wirkung

PO-1 is a cell-permeable fluorescent sensor that is highly selective for detecting the presence of H2O2 in living cells.

Rechtliche Hinweise

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. The availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Boronate-Based Fluorescent Probes: Imaging Hydrogen Peroxide in Living Systems
Lin V S, et al.
Methods in Enzymology, 526, 19-43 (2013)
Mobile gene silencing in Arabidopsis is regulated by hydrogen peroxide
Liang D, et al.
PeerJ, 2, e701-e701 (2014)
Sandeep Saxena et al.
Nature communications, 10(1), 4400-4400 (2019-09-29)
A surveillance system in mammals constantly monitors cell activity to protect against aberrant proliferation in response to damage, injury and oncogenic stress. Here we isolate and culture connective tissue fibroblasts from highly regenerative mammals (Acomys and Oryctolagus) to determine how

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