SML0651

OAC1

≥98% (HPLC)

• Synonym(e): N-1H-Pyrrolo[2,3-c]pyridin-5-yl-benzamide
• Empirische Formel (Hill-System): C₁₄H₁₁N₃O
• CAS-Nummer: 300586-90-7
• Molekulargewicht: 237.26
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: white to beige
• Löslichkeit: DMSO: 20 mg/mL, clear
• Lagertemp.: 2-8°C
• InChI: 1S/C14H11N3O/c18-14(10-4-2-1-3-5-10)17-13-8-11-6-7-15-12(11)9-16-13/h1-9,15H,(H,16,17,18)
• InChIKey: HWJRIFZDXJKJJN-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

OAC1 enhances iPSC reprogramming efficiency by enhancing Oct4 and Nanog driven gene expression. Treatment of mouse embryonic fibroblasts transduced with Oct2, Sox2, Klf4 and c-myc displayed a two-fold increase in the formation of ESC-like clones. OAC1 treated cells display a hypomethylated state of Oct4 promoter DNA.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable