SML0588

CP-94,253 dihydrochloride

≥98% (HPLC)

• Synonym(e): 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride, 3- (1,2,5,6-Tetrahydro-4-pyridyl)-5-propoxypyrrolo[3, 2-b] pyridine hydrochloride, 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride, CP-94253 hydrochloride
• Empirische Formel (Hill-System): C₁₅H₁₉N₃O · 2HCl
• CAS-Nummer: 131084-35-0
• Molekulargewicht: 330.25
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825567
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 15 mg/mL, clear
• Lagertemp.: room temp
• SMILES String: Cl.Cl.CCCOc1ccc2[nH]cc(C3=CCNCC3)c2n1
• InChI: 1S/C15H19N3O.2ClH/c1-2-9-19-14-4-3-13-15(18-14)12(10-17-13)11-5-7-16-8-6-11;;/h3-5,10,16-17H,2,6-9H2,1H3;2*1H
• InChIKey: HGFPLQPNCZQRLO-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

CP-94,253 is a potent and selective serotonin 5-HT1B receptor agonist with approximately 25x and 40x selectivity over the closely related 5-HT1D and 5-HT1A receptors. Ki values are 89, 2, 860, 49 and 1,600 nM for 5-HT1A, 5-HT1B, 5-HT1C, 5-HT1D and 5-HT2 receptors respectively. CP-94,253 was found to be anxiolytic in animal models; dose-dependently enhanced reinforcing effects of cocaine (self-administration);and reduced food intake.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 - H315 - H319 - H335
• P-Sätze: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable