SML0367

VK3-OCH3

≥98% (HPLC)

• Synonym(e): 2-[(2-Methoxy)ethylthio]-3-methyl-1,4-naphthoquinone
• Empirische Formel (Hill-System): C₁₄H₁₄O₃S
• CAS-Nummer: 255906-59-3
• Molekulargewicht: 262.32
• MDL-Nummer: MFCD22575003
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825368
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: light orange to dark orange
• Löslichkeit: DMSO: 10 mg/mL (clear solution)
• Lagertemp.: 2-8°C
• SMILES String: COCCSC1=C(C)C(=O)c2ccccc2C1=O
• InChI: 1S/C14H14O3S/c1-9-12(15)10-5-3-4-6-11(10)13(16)14(9)18-8-7-17-2/h3-6H,7-8H2,1-2H3
• InChIKey: JTCRCMIBIBLUOK-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

VK3-OCH3 is an analog of Vitamin K3 (Menadione) with potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards normal cells. VK3-OCH3 is believed to act through up-regulation of heme oxygenase (HO)-1.

Sicherheitshinweise

• Piktogramme: GHS09
• Signalwort: Warning
• H-Sätze: H400
• P-Sätze: P273 - P391 - P501
• Gefahreneinstufungen: Aquatic Acute 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable