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Merck

SCP0156

Sigma-Aldrich

Gly-Arg-Ala-Asp-Ser-Pro (GRADSP)

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About This Item

Empirische Formel (Hill-System):
C23H39N9O10
Molekulargewicht:
601.61
UNSPSC-Code:
12352209
NACRES:
NA.32

Assay

≥95% (HPLC)

Form

lyophilized

Zusammensetzung

Peptide Content, ≥65%

Lagerbedingungen

protect from light

Lagertemp.

−20°C

Amino Acid Sequence

Gly-Arg-Ala-Asp-Ser-Pro

Allgemeine Beschreibung

GRADSP, an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as RGDS (Arg-Gly-Asp-Ser) and GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro).
Gly-Arg-Ala-Asp-Ser-Pro (GRADSP), an integrin non-binding peptide, may be used as a negative control in studies with integrin-blocking peptides such as Arg-Gly-Asp-Ser (RGDS) and Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP).

Anwendung

Gly-Arg-Ala-Asp-Ser-Pro (GRADSP) has been used as a negative control to observe the role of the Arg-Gly-Asp (RGD)-binding integrins in Gal-3-mediated cell adhesion. It has also been used as a control peptide to block the RGD-dependent integrins/integrin signaling.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

U Stäubli et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(9), 3460-3469 (1998-05-09)
The integrin antagonist Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) was applied by local ejection to one of two recording sites in hippocampal slices at various times before and after long-term potentiation (LTP) was induced at both sites with theta burst stimulation. Applications 10 min
Major role of the extracellular matrix in airway smooth muscle phenotype plasticity
Dekkers BGJ
American Journal of Respiratory and Critical Care Medicine, 181(6), 556-565 (2010)
Julia Dotterweich et al.
Cell communication and signaling : CCS, 12, 36-36 (2014-06-27)
CCN family member 1 (CCN1), also known as cysteine-rich angiogenic inducer 61 (CYR61), belongs to the extracellular matrix-associated CCN protein family. The diverse functions of these proteins include regulation of cell migration, adhesion, proliferation, differentiation and survival/apoptosis, induction of angiogenesis
Antonín Sedlář et al.
International journal of molecular sciences, 22(10) (2021-06-03)
Galectin-3 (Gal-3) is a β-galactoside-binding protein that influences various cell functions, including cell adhesion. We focused on the role of Gal-3 as an extracellular ligand mediating cell-matrix adhesion. We used human adipose tissue-derived stem cells and human umbilical vein endothelial

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