SAB5700651

Anti-TGFBR1 antibody produced in rabbit

• Synonym(e): AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TBR-i, TBRI, TGFBR1, TGFR-1, tbetaR-I
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 47; 55; 56
• Speziesreaktivität: human, mouse, rat
• Konzentration: 4.38 mg/ml
• Methode(n): immunofluorescence: 1:50-1:100; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:2000
• UniProt-Hinterlegungsnummer: P36897
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TGFBR1(7046)

Beschreibung

Allgemeine Beschreibung

The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 34-124 of human TGFBR1 (NP_001124388.1).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable