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Merck

SAB5500162

Sigma-Aldrich

Anti-PI3K P85 antibody, Rabbit monoclonal

clone SP62, recombinant, expressed in proprietary host, affinity isolated antibody

Synonym(e):

Anti-AGM7, Anti-GRB1, Anti-IMD36, Anti-p85, Anti-p85-ALPHA

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Rekombinant

expressed in proprietary host

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

SP62, monoclonal

Speziesreaktivität

human (tested)

Speziesreaktivität (Voraussage durch Homologie)

frog, bovine, rat, mouse

Methode(n)

flow cytometry: 1:100
immunohistochemistry: 1:100

Isotyp

IgG

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... PIK3R1(5295)

Allgemeine Beschreibung

Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110kDa catalytic subunit and a regulatory subunit of either 85, 55, or 50kDa. PI3K p85 is a 85kDa regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.

Immunogen

Synthetic peptide from N-terminus of human PI3K p85.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Hongbin Wang et al.
Molecular medicine reports, 16(3), 3351-3356 (2017-07-18)
Breast cancer has one of the highest incidences in females worldwide. Girdin is a novel actin‑binding protein, that induces cell migration and angiogenesis. However, a systematic study of Girdin function in distinct subtypes of breast cancer has not been reported
Cheng Zhang et al.
Oncology letters, 13(4), 2059-2070 (2017-04-30)
Human bone marrow stromal cells (hBMSCs) may contribute to the growth of tyrosine kinase inhibitor (TKI)-resistant chronic myelogenous leukemia (CML). However, there are certain differences in biology between CML and Philadelphia-positive acute lymphoblastic leukemia (Ph+ ALL). Little is known about

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