SAB4702006

Monoclonal Anti-Cytokeratin 19 FITC produced in mouse

• Synonym(e): CK19, CYK19, K19, K1CS, KRT19
• UNSPSC-Code: 12352203

Eigenschaften

• Konjugat: FITC conjugate
• Qualitätsniveau: 100
• Antikörper-Produkttyp: primary antibodies
• Klon: A53-B/A2, monoclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Konzentration: 1 mg/ml
• Methode(n): flow cytometry: suitable
• Isotyp: IgG2a
• UniProt-Hinterlegungsnummer: P08727
• Lagertemp.: 2-8°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... KRT19(3880)

Beschreibung

Allgemeine Beschreibung

Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. They are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.

Spezifität

The mouse monoclonal antibody A53-B/A2 recognizes the rod domain of cytokeratin 19 (40 kDa), an intracellular antigen constituting intermmediate cytoskeleton filaments. Cytokeratin 19 is not expressed in hepatocytes; it is often co-expressed with cytokeratin 7.

Immunogen

MCF-7 human breast adenocarcinoma cell line

Physikalische Form

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Angaben zur Herstellung

Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Lagerung und Haltbarkeit

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Sonstige Hinweise

The antibody solution should be gently mixed before use.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable