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SAB4700393

Sigma-Aldrich

Monoclonal Anti-CD11c-PE antibody produced in mouse

clone BU15, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Anti-ITGAX

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.44

Biologische Quelle

mouse

Qualitätsniveau

100

Konjugat

phycoerythrin (R-PE) conjugate

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

BU15, monoclonal

Form

buffered aqueous solution

Speziesreaktivität

monkey, canine, human

Methode(n)

flow cytometry: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_000887.3

UniProt-Hinterlegungsnummer

P20702

Versandbedingung

wet ice

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... ITGAX(3687)

Allgemeine Beschreibung

The antibody BU15 reacts with CD11c (alphaX, p150), a 150 kDa integrin expressed mainly on dendritic cells and tissue macrophages.

Immunogen

Dendritic cells of synovial fluid

Anwendung

The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
527892
527891
525346
518557
524310

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Die Dokumentenbibliothek aufrufen

Ping Chen et al.
Transplant international : official journal of the European Society for Organ Transplantation, 27(10), 1069-1076 (2014-06-26)
Reduced pretransplant blood myeloid dendritic cell (mDC) levels are associated with post-transplant BK viremia and cytomegalovirus (CMV) disease after kidney transplantation. To elucidate potential mechanisms by which mDC levels might influence these outcomes, we studied the association of mDC levels
Ji Wang et al.
Nature communications, 5, 4447-4447 (2014-07-19)
There is an urgent need of adjuvants for cutaneous vaccination. Here, we report that micro-sterile inflammation induced at inoculation sites can augment immune responses to influenza vaccines in animal models. The inoculation site is briefly illuminated with a handheld, non-ablative
Chanchal Sadhu et al.
Journal of immunoassay & immunochemistry, 29(1), 42-57 (2007-12-18)
Functions and binding properties of four CD11c-specific mAbs are described here. The mAb 496B stimulated, while 496K inhibited ligand binding of CD11c. The stimulatory mAb, 496B, as well as the inhibitory mAbs BU15 and 496 K appear to act allosterically
Akiko Kurishima et al.
Journal of gastroenterology, 49(10), 1367-1377 (2013-10-01)
Dendritic cells (DCs) may play an important role in forms of inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. DCs are generally recognized as initiators of acquired immunity and also serve as regulators of both innate and

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