SAB4504671

Anti-phospho-DDR1 (pTyr⁵¹³) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-CAK, Anti-CD167, Anti-DDR, Anti-EDDR1, Anti-HGK2, Anti-MCK10, Anti-NEP, Anti-NTRK4, Anti-PTK3, Anti-RTK6, Anti-TRKE
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 101 kDa
• Speziesreaktivität: rat, mouse, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:10000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: Q08345
• UniProt-Hinterlegungsnummer: Q08345
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr513)
• Angaben zum Gen: human ... DDR1(780)

Beschreibung

Allgemeine Beschreibung

Discoidin domain receptor I (DDR1) is a receptor tyrosine kinase (RTK)/collagen-activated tyrosine kinase, that is located on human chromosome 6p21.

Immunogen

The antiserum was produced against synthesized peptide derived from human DDR1 around the phosphorylation site of Tyr513.

Immunogen Range: 479-528

Biochem./physiol. Wirkung

Discoidin domain receptor I (DDR1) plays important roles in several cancers. In renal cancer cells, DDR1 promotes epithelial to mesenchymal transition. It also increases invasion and metastasis of gastric cancer through epithelial-mesenchymal transition.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable