SAB4503996

Anti-phospho-Synuclein (pSer¹²⁹) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-NACP, Anti-PARK1, Anti-PARK4, Anti-PD1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 14 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:1000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: P37840
• UniProt-Hinterlegungsnummer: P37840
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer129)
• Angaben zum Gen: human ... SNCA(6622)

Beschreibung

Allgemeine Beschreibung

The SNCA (synuclein α) gene codes for a 140-amino acid protein α-synuclein, that is mapped to human chromosome 4q21-23.

Immunogen

The antiserum was produced against synthesized peptide derived from human Synuclein around the phosphorylation site of Ser129.

Immunogen Range: 91-140

Anwendung

Anti-phospho-Synuclein (pSer129) antibody has been used in immunohistochemistry.

Biochem./physiol. Wirkung

Accumulation of α-synuclein in oligodendrocytes results in the loss of myelin and causes neurodegeneration, leading to multiple system atrophy. Synuclein-α is known to induce oligodendrocyte maturation. Mutations in the SNCA result in parkinson disease.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable